BERG Announces FDA Orphan-Drug Designation of BPM31510 for the Treatment of Pancreatic Cancer

BERG, a Boston-based biopharmaceutical company that merges biology with technology to map the nature of diseases, today announced the U.S. Food and Drug Administration (FDA) has granted orphan-drug designation to the Company’s leading product candidate BPM31510, for the treatment of pancreatic cancer. “The FDA’s orphan-drug designation marks an important milestone for BERG,” said Niven R.…

A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells

BMC Genomics. (2017) 18: 987 Authors: Jialiang Yang, Jacob Hagen, Kalyani V. Guntur, Kimaada Allette, Sarah Schuyler, Jyoti Ranjan, Francesca Petralia, Stephane Gesta, Robert Sebra, Milind Mahajan, Bin Zhang, Jun Zhu, Sander Houten, Andrew Kasarskis, Vivek K. Vishnudas, Viatcheslav R. Akmaev, Rangaprasad Sarangarajan, Niven R. Narain, Eric E. Schadt, Carmen A. Argmann, Zhidong Tu Exosomes…

Human CCDC47 sandwich immunoassay development with electrochemiluminescence technology

Journal of Immunological Methods, 2018, 452:12 Authors: Wenfang S. Wu, Liang Zhu, Saurabh Patil, Karthiga Gokula, Sean Reilly, Joyce Chan, Poornima Tekumalla, Vivek Vishnudas, Michael A.Kiebish, Rangaprasad Sarangarajana, Viatcheslav R. Akmaev, Mark D.Kellogg, Niven R.Narain Coiled-Coil Domain Containing 47 (CCDC47) is an endoplasmic reticulum (ER) transmembrane protein involved in calcium signaling through utilization of its…